Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Cupric Acetate may cause a skin allergy. If allergy develops, very low future exposure can cause itching and a skin rash. Ingestion: May cause irritation of the digestive tract. May cause liver and kidney damage. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: Adverse reproductive effects have been reported in animals. Cupric Acetate has caused adverse reproductive effects in experimental animals.